TOXICITY STUDIES

Bacterial Reverse Mutation Assay (as per OECD Guidelines)

Bacterial Reverse Mutation Assay was conducted for DigeZyme using Salmonella typhimurium tester strains TA98, TA100, TA102, TA1535 and TA1537 by plate incorporation method.

DigeZyme® gave a negative response in the presence and absence of Aroclor 1254 induced rat liver S9 in the assay up to 5000 µg/plate.

DigeZyme® was confirmed non mutagenic in the Bacterial Reverse Mutation Assay with an Independent Repeat assay.

Composition

Alpha-Amylase


Neutral protease


Cellulase


Lactase


Lipase